The Air Force has been looking into a number of reports that pilots experienced "hypoxia-like symptoms" aboard F-22s since April 2008. Hypoxia is oxygen deficiency. The Air Force reports 25 cases of such systems, including 11 since September, when the service cleared the F-22 fleet to return to flight after a four-month grounding. The fleet was grounded in May 2011 so the service could check the hypoxia reports, but the order was lifted in September under a "return to fly" plan, with equipment modifications and new rules including daily inspections of the life-support systems. "Early on in the return to fly we had five maintainers that reported hypoxia symptoms," Gen. Daniel Wyman, command surgeon for the Air Combat Command, said during a conference call with reporters Wednesday.

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